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Critical Role of Interleukin-11 in Isoflurane-mediated Protection against Ischemic Acute Kidney Injury in Mice

BACKGROUND: Isoflurane releases renal tubular transforming growth factor-beta 1 (TGF-β1) and protects against ischemic acute kidney injury (AKI). Recent studies suggest that TGF-β1 can induce a cytoprotective cytokine interleukin (IL)-11. Here, we tested the hypothesis that isoflurane protects again...

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Detalhes bibliográficos
Main Authors: Ham, Ahrom, Kim, Mihwa, Kim, Joo Yun, Brown, Kevin M., Yeh, James, D’Agati, Vivette D., Lee, H. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867581/
https://ncbi.nlm.nih.gov/pubmed/24037316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3182a950da
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