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Inhibition of the in vivo parathyroid hormone-mediated calcemic response in rats by a synthetic hormone antagonist.

The parathyroid hormone (PTH) analog, [Tyr34]bovine PTH-(7-34)-amide, can inhibit the PTH-mediated elevation of plasma calcium in thyroparathyroidectomized rats in vivo. The analog is devoid of PTH-like agonist activity in this system. Repeated doses of analog inhibit the animal's calcemic resp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Doppelt, S H, Neer, R M, Nussbaum, S R, Federico, P, Potts, J T, Rosenblatt, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386758/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3463984/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7557
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