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Recombination within the myelin basic protein gene created the dysmyelinating shiverer mouse mutation.

Shiverer (shi) is an autosomal recessive mutation in the mouse characterized by an almost total lack of central nervous system myelin. While small amounts of other myelin components are present in the brain of the shi mouse, the four forms of myelin basic protein (MBP) are not detectable. Previous i...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Molineaux, S M, Engh, H, de Ferra, F, Hudson, L, Lazzarini, R A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2429310/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7542
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