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Correlative and quantitative (1)H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats

Type 1 diabetes was induced in Sprague–Dawley rats using streptozotocin. Rat urine samples (8 diabetic and 10 control) were analyzed by (1)H nuclear magnetic resonance (NMR) spectroscopy. The derived metabolites using univariate and multivariate statistical analysis were subjected to correlative ana...

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Detalhes bibliográficos
Main Authors: Zhang, Shucha, Gowda, G.A. Nagana, Asiago, Vincent, Shanaiah, Narasimhamurthy, Barbas, Coral, Raftery, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867451/
https://ncbi.nlm.nih.gov/pubmed/18775407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.07.041
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