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Decision-Tree Based Model Analysis for Efficient Identification of Parameter Relations Leading to Different Signaling States

In systems biology, a mathematical description of signal transduction processes is used to gain a more detailed mechanistic understanding of cellular signaling networks. Such models typically depend on a number of parameters that have different influence on the model behavior. Local sensitivity anal...

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Detalles Bibliográficos
Main Authors: Koch, Yvonne, Wolf, Thomas, Sorger, Peter K., Eils, Roland, Brors, Benedikt
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867358/
https://ncbi.nlm.nih.gov/pubmed/24367526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082593
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