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ADARs, Viruses and Innate Immunity
Double-stranded RNA (dsRNA) functions both as a substrate of ADARs and also as a molecular trigger of innate immune responses. ADARs, adenosine deaminases that act on RNA, catalyze the deamination of adenosine (A) to produce inosine (I) in dsRNA. ADARs thereby can destablize RNA structures, because...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867276/ https://ncbi.nlm.nih.gov/pubmed/21809195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2011_148 |
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