Age-associated Decrease in Toll-like Receptor Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response()

We evaluated Toll-like receptor (TLR) function in primary human dendritic cells from 104 young (age 21–30) and older (≥ 65 years) individuals. We used multicolor flow cytometry and intracellular cytokine staining of myeloid (mDC) and plasmacytoid (pDC) DCs and found substantial decreases in older, c...

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Detaylı Bibliyografya
Asıl Yazarlar: Panda, Alexander, Qian, Feng, Mohanty, Subhasis, van Duin, David, Newman, Frances K., Zhang, Lin, Chen, Shu, Towle, Virginia, Belshe, Robert B., Fikrig, Erol, Allore, Heather G., Montgomery, Ruth R., Shaw, Albert C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867271/
https://ncbi.nlm.nih.gov/pubmed/20100933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901022
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