ATP-independent type II topoisomerase from trypanosomes.

We have characterized in Trypanosoma cruzi a DNA topoisomerase capable of decatenating complex trypanosomal kinetoplast DNA networks in the absence of ATP. The enzymatic activity requires Mg2+ and K+. Using a defined DNA topoisomer we showed that the linking number changes by steps of 2, which chara...

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Bibliografiske detaljer
Main Authors: Douc-Rasy, S, Kayser, A, Riou, J F, Riou, G
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC386673/
https://ncbi.nlm.nih.gov/pubmed/3020537
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