Targeted Drug Delivery with Focused Ultrasound-Induced Blood-Brain Barrier Opening Using Acoustically-Activated Nanodroplets

Focused ultrasound (FUS) in the presence of systemically administered microbubbles has been shown to locally, transiently and reversibly increase the permeability of the blood-brain barrier (BBB), thus allowing targeted delivery of therapeutic agents in the brain for the treatment of central nervous...

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Hauptverfasser: Chen, Cherry C., Sheeran, Paul S., Wu, Shih-Ying, Olumolade, Oluyemi O., Dayton, Paul A., Konofagou, Elisa E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866692/
https://ncbi.nlm.nih.gov/pubmed/24096019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.09.025
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