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Defining a new vision for the retinoblastoma gene: report from the 3rd International Rb Meeting
The retinoblastoma tumor suppressor (Rb) pathway is mutated in most, if not all human tumors. In the G0/G1 phase, Rb and its family members p107 and p130 inhibit the E2F family of transcription factors. In response to mitogenic signals, Cyclin-dependent kinases (CDKs) phosphorylate Rb family members...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3866465/ https://ncbi.nlm.nih.gov/pubmed/24257515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-8-13 |
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