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Encapsulation of adriamycin in human erythrocytes.

Adriamycin (doxorubicin) was encapsulated in human erythrocytes by means of a dialysis technique involving transient hypotonic hemolysis followed by isotonic resealing. Up to 1.6 mg of the drug was entrapped per ml of packed erythrocytes, with the efficiency of encapsulation being 60-80%. In vitro i...

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Bibliographic Details
Main Authors: De Flora, A, Benatti, U, Guida, L, Zocchi, E
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC386646/
https://ncbi.nlm.nih.gov/pubmed/3462740
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