Acquired drug resistance conferred by a KRAS gene mutation following the administration of cetuximab: a case report

BACKGROUND: Although a number of studies have reported acquired drug resistance due to administration of epidermal growth factor receptor antibody inhibitors, the underlying causes of this phenomenon remain unclear. CASE PRESENTATION: Here we report a case of a 75-year-old man with liver metastasis...

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Autors principals: Osumi, Hiroki, Matsusaka, Satoshi, Shinozaki, Eiji, Suenaga, Mitsukuni, Mingyon, Mun, Saiura, Akio, Ueno, Masashi, Mizunuma, Nobuyuki, Yamaguchi, Toshiharu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Case Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866299/
https://ncbi.nlm.nih.gov/pubmed/24304820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-508
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