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Frameshift mutations produced by proflavin in bacteriophage T4: specificity within a hotspot.

Frameshift mutations were induced by proflavin in the rIIB gene of bacteriophage T4. rIIB DNA from each of 48 independent frameshifts was inserted into M13mp8 and sequenced. Two-thirds of the frameshifts (33/48) lie contiguous to one another in 10 base pairs of the rIIB sequence. This hotspot differ...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ripley, L S, Clark, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386629/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3462738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.18.6954
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