Gene Expression Profiling of Early Hepatic Stellate Cell Activation Reveals a Role for Igfbp3 in Cell Migration

BACKGROUND: Scarring of the liver is the result of prolonged exposure to exogenous or endogenous stimuli. At the onset of fibrosis, quiescent hepatic stellate cells (HSCs) activate and transdifferentiate into matrix producing, myofibroblast-like cells. AIM AND METHODS: To identify key players during...

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Detalhes bibliográficos
Principais autores: Mannaerts, Inge, Schroyen, Ben, Verhulst, Stefaan, Van Lommel, Leentje, Schuit, Frans, Nyssen, Marc, van Grunsven, Leo A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866247/
https://ncbi.nlm.nih.gov/pubmed/24358328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084071
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