Gene Expression Profiling of Early Hepatic Stellate Cell Activation Reveals a Role for Igfbp3 in Cell Migration

BACKGROUND: Scarring of the liver is the result of prolonged exposure to exogenous or endogenous stimuli. At the onset of fibrosis, quiescent hepatic stellate cells (HSCs) activate and transdifferentiate into matrix producing, myofibroblast-like cells. AIM AND METHODS: To identify key players during...

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主要な著者: Mannaerts, Inge, Schroyen, Ben, Verhulst, Stefaan, Van Lommel, Leentje, Schuit, Frans, Nyssen, Marc, van Grunsven, Leo A.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866247/
https://ncbi.nlm.nih.gov/pubmed/24358328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084071
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