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Dendropanoxide Induces Autophagy through ERK1/2 Activation in MG-63 Human Osteosarcoma Cells and Autophagy Inhibition Enhances Dendropanoxide-Induced Apoptosis

Anticancer effects of dendropanoxide (DP) newly isolated from leaves and stem of Dendropanax morbifera Leveille were firstly investigated in this study. DP inhibited cell proliferation and induced apoptosis in dose- and time-dependent manner in MG-63 human osteosarcoma cells, which was dependent on...

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Detalhes bibliográficos
Main Authors: Lee, Ji-Won, Kim, Kyoung-Sook, An, Hyun-Kyu, Kim, Cheorl-Ho, Moon, Hyung-In, Lee, Young-Choon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866153/
https://ncbi.nlm.nih.gov/pubmed/24358301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083611
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