Hyperoxia Exposure Impairs Nephrogenesis in the Neonatal Rat: Role of HIF-1α

Preterm neonates are exposed at birth to high oxygen concentrations relative to the intrauterine environment. We have previously shown in a rat model that a hyperoxic insult results in a reduced nephron number in adulthood. Therefore, the aim of this study was to determine the effects of transient n...

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Detalhes bibliográficos
Main Authors: Popescu, Constantin R., Sutherland, Megan R., Cloutier, Anik, Benoît, Geneviève, Bertagnolli, Mariane, Yzydorczyk, Catherine, Germain, Nathalie, Phan, Véronique, Lelièvre-Pegorier, Martine, Sartelet, Hervé, Nuyt, Anne Monique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866112/
https://ncbi.nlm.nih.gov/pubmed/24358181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082421
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