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Enhanced effects of amphetamine but reduced effects of the hallucinogen, 5-MeO-DMT, on locomotor activity in 5-HT(1A) receptor knockout mice: Implications for schizophrenia

Serotonin-1A (5-HT(1A)) receptors may play a role in schizophrenia and the effects of certain antipsychotic drugs. However, the mechanism of interaction of 5-HT(1A) receptors with brain systems involved in schizophrenia, remains unclear. Here we show that 5-HT(1A) receptor knockout mice display enha...

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Detalhes bibliográficos
Main Authors: van den Buuse, Maarten, Ruimschotel, Emma, Martin, Sally, Risbrough, Victoria B., Halberstadt, Adam L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866100/
https://ncbi.nlm.nih.gov/pubmed/21501627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.04.001
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