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Obstructive Sleep Apnea and Intermittent Hypoxia Increase Expression of Dual Specificity Phosphatase 1

OBJECTIVE: Dual specificity phosphatase 1 (DUSP1) inhibits mitogen activated protein kinase activity, and is activated by several stimuli such as sustained hypoxia, oxidative stress, and hormones. However, the effect of intermittent hypoxia is not known. The aim of this study was to evaluate the rol...

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Detalhes bibliográficos
Main Authors: Hoffmann, Michal S., Singh, Prachi, Wolk, Robert, Narkiewicz, Krzysztof, Somers, Virend K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865929/
https://ncbi.nlm.nih.gov/pubmed/24267255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2013.09.033
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