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Chemical Diversification of Sialic Acid Glycosides by Stereospecific, Chemoselective Deamination

[Image: see text] Nitrosation of peracetylated NeuAc glycosides followed by treatment with sodium trifluoroethoxide and then a suitable nucleophile enables late stage modification of sialic acid glycosides with stereospecific replacement of the acetamido functionality.

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Bibliografiske detaljer
Main Authors: Navuluri, Chandrasekhar, Crich, David
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865865/
https://ncbi.nlm.nih.gov/pubmed/24038615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201303781
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