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Formation of a translational inhibitor by interaction of phospholipid with the eukaryotic initiation factor 2.

The polypeptide chain initiation factor 2 (eIF-2) binds phospholipid (PL) and becomes a potent inhibitor of translation in hemin-supplemented reticulocyte lysates. This binding is markedly reduced by prior treatment of eIF-2 with N-ethylmaleimide. Although PL is probably bound by all three eIF-2 sub...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: de Haro, C, de Herreros, A G, Ochoa, S
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1986
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3462720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.18.6711
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