Formation of a translational inhibitor by interaction of phospholipid with the eukaryotic initiation factor 2.

The polypeptide chain initiation factor 2 (eIF-2) binds phospholipid (PL) and becomes a potent inhibitor of translation in hemin-supplemented reticulocyte lysates. This binding is markedly reduced by prior treatment of eIF-2 with N-ethylmaleimide. Although PL is probably bound by all three eIF-2 sub...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: de Haro, C, de Herreros, A G, Ochoa, S
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1986
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC386579/
https://ncbi.nlm.nih.gov/pubmed/3462720
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