Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

We have examined the regulation of somatostatin gene expression by cAMP in PC12 rat pheochromocytoma cells transfected with the rat somatostatin gene. Forskolin at 10 microM caused a 4-fold increase in somatostatin mRNA levels within 4 hr of treatment in stably transfected cells. Chimeric genes cont...

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Bibliographische Detailangaben
Hauptverfasser: Montminy, M R, Sevarino, K A, Wagner, J A, Mandel, G, Goodman, R H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC386573/
https://ncbi.nlm.nih.gov/pubmed/2875459
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