Leptomeningeal Cells Transduce Peripheral Macrophages Inflammatory Signal to Microglia in Reponse to Porphyromonas gingivalis LPS

We report here that the leptomeningeal cells transduce inflammatory signals from peripheral macrophages to brain-resident microglia in response to Porphyromonas gingivalis (P.g.) LPS. The expression of Toll-like receptor 2 (TLR2), TLR4, TNF-α, and inducible NO synthase was mainly detected in the gin...

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Detalhes bibliográficos
Main Authors: Liu, Yicong, Wu, Zhou, Zhang, Xinwen, Ni, Junjun, Yu, Weixian, Zhou, Yanmin, Nakanishi, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865690/
https://ncbi.nlm.nih.gov/pubmed/24363500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/407562
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