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Nicotinic acetylcholine receptor contains multiple binding sites: evidence from binding of alpha-dendrotoxin.

We have studied the stoichiometry of the binding of the long alpha-neurotoxins from the venom of Dendroaspis viridis (alpha-dendrotoxin) and Naja naja siamensis (alpha-cobratoxin) to the membrane-bound acetylcholine receptor (AcChoR) from Torpedo californica electric organ. The number of toxin molec...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Conti-Tronconi, B M, Raftery, M A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1986
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386561/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3462717/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6646
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