Correction of adenosine deaminase deficiency in cultured human T and B cells by retrovirus-mediated gene transfer.
A retroviral vector called SAX, containing the cloned human cDNA for adenosine deaminase (ADA), has been constructed and used to introduce the ADA gene into cultured T- and B-lymphocyte lines derived from patients with ADA deficiency. DNA analysis showed that the SAX vector was inserted intact into...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1986
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3489233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6563 |
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