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Correction of adenosine deaminase deficiency in cultured human T and B cells by retrovirus-mediated gene transfer.
A retroviral vector called SAX, containing the cloned human cDNA for adenosine deaminase (ADA), has been constructed and used to introduce the ADA gene into cultured T- and B-lymphocyte lines derived from patients with ADA deficiency. DNA analysis showed that the SAX vector was inserted intact into...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1986
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3489233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6563 |
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