Kernel canonical correlation analysis for assessing gene–gene interactions and application to ovarian cancer

Although single-locus approaches have been widely applied to identify disease-associated single-nucleotide polymorphisms (SNPs), complex diseases are thought to be the product of multiple interactions between loci. This has led to the recent development of statistical methods for detecting statistic...

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Huvudupphovsmän: Larson, Nicholas B, Jenkins, Gregory D, Larson, Melissa C, Vierkant, Robert A, Sellers, Thomas A, Phelan, Catherine M, Schildkraut, Joellen M, Sutphen, Rebecca, Pharoah, Paul P D, Gayther, Simon A, Wentzensen, Nicolas, Goode, Ellen L, Fridley, Brooke L
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865403/
https://ncbi.nlm.nih.gov/pubmed/23591404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.69
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