Intracellular potassium depletion in IM-9 lymphocytes suppresses the slowly dissociating component of human growth hormone binding and the down-regulation of its receptors but does not affect insulin receptors.

We have investigated whether the slowly dissociating component of insulin and human growth hormone (hGH) binding and the homologous down-regulation of their receptors in IM-9 cultured human lymphocytes are due to distinct conformations of the receptor or, rather, to a redistribution within the cell....

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Ilondo, M M, Courtoy, P J, Geiger, D, Carpentier, J L, Rousseau, G G, De Meyts, P
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1986
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386523/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3018733/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6460
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