No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women

OBJECTIVE: Sex-steroid hormones play a role in colorectal cancer (CRC) development, but little is known about their influence on tumor progression and metastasis. Because catechol-O-methyltransferase activity (COMT; 22q11.21) is an important component of estrogen-mediated carcinogenesis, we hypothes...

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Détails bibliographiques
Auteurs principaux: Passarelli, Michael N., Newcomb, Polly A., Makar, Karen W., Burnett-Hartman, Andrea N., Phipps, Amanda I., David, Sean P., Hsu, Li, Harrison, Tabitha A., Hutter, Carolyn M., Duggan, David J., White, Emily, Chan, Andrew T., Peters, Ulrike
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865220/
https://ncbi.nlm.nih.gov/pubmed/23880798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0b013e31829e498d
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