A Novel Cell-Sheet Technology That Achieves Durable Factor VIII Delivery in a Mouse Model of Hemophilia A

Gene- or cell-based therapies aimed at creating delivery systems for coagulation factor VIII (FVIII) protein have emerged as promising options for hemophilia A treatment. However, several issues remain to be addressed regarding the efficacies and adverse events of these new classes of therapies. To...

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Bibliographic Details
Main Authors: Tatsumi, Kohei, Sugimoto, Mitsuhiko, Lillicrap, David, Shima, Midori, Ohashi, Kazuo, Okano, Teruo, Matsui, Hideto
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865186/
https://ncbi.nlm.nih.gov/pubmed/24358271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083280
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