Inhibition of oligosaccharide processing and membrane morphogenesis in retinal rod photoreceptor cells.
Castanospermine (Cas), an inhibitor of alpha-glucosidase I, blocks "trimming" of the N-linked oligosaccharide Glc3Man9GlcNAc2, thus preventing normal glycoprotein maturation. With use of a dual-label protocol, Xenopus retinas incubated in the presence of Cas exhibited at least a 2.3-fold increase in...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1986
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386518/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2944109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6435 |
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