Inhibition of oligosaccharide processing and membrane morphogenesis in retinal rod photoreceptor cells.

Castanospermine (Cas), an inhibitor of alpha-glucosidase I, blocks "trimming" of the N-linked oligosaccharide Glc3Man9GlcNAc2, thus preventing normal glycoprotein maturation. With use of a dual-label protocol, Xenopus retinas incubated in the presence of Cas exhibited at least a 2.3-fold increase in...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Fliesler, S J, Rayborn, M E, Hollyfield, J G
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1986
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386518/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2944109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6435
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