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Inositol cyclic triphosphate [inositol 1,2-(cyclic)-4,5-triphosphate] is formed upon thrombin stimulation of human platelets.

Cleavage of polyphosphoinositides in vitro by phospholipase C results in formation of both cyclic and noncyclic inositol phosphates. We have now isolated the cyclic product of phosphatidylinositol 4,5-bisphosphate cleavage, inositol 1,2(cyclic)-4,5-triphosphate [cIns(1:2,4,5)P3], from thrombin-treat...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ishii, H, Connolly, T M, Bross, T E, Majerus, P W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3018731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.17.6397
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