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Development and Application of Genomic Control Methods for Genome-Wide Association Studies Using Non-Additive Models

Genome-wide association studies (GWAS) comprise a powerful tool for mapping genes of complex traits. However, an inflation of the test statistic can occur because of population substructure or cryptic relatedness, which could cause spurious associations. If information on a large number of genetic m...

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Detalhes bibliográficos
Main Authors: Tsepilov, Yakov A., Ried, Janina S., Strauch, Konstantin, Grallert, Harald, van Duijn, Cornelia M., Axenovich, Tatiana I., Aulchenko, Yurii S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864791/
https://ncbi.nlm.nih.gov/pubmed/24358113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081431
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