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Development and Application of Genomic Control Methods for Genome-Wide Association Studies Using Non-Additive Models
Genome-wide association studies (GWAS) comprise a powerful tool for mapping genes of complex traits. However, an inflation of the test statistic can occur because of population substructure or cryptic relatedness, which could cause spurious associations. If information on a large number of genetic m...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864791/ https://ncbi.nlm.nih.gov/pubmed/24358113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081431 |
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