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Interferon-β Induced microRNA-129-5p Down-Regulates HPV-18 E6 and E7 Viral Gene Expression by Targeting SP1 in Cervical Cancer Cells

Infection by human papillomavirus (HPV) can cause cervical intraepithelial neoplasia (CIN) and cancer. Down-regulation of E6 and E7 expression may be responsible for the positive clinical outcomes observed with IFN treatment, but the molecular basis has not been well determined. As miRNAs play an im...

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Detalhes bibliográficos
Main Authors: Zhang, Jiarong, Li, Shuangdi, Yan, Qin, Chen, Xiaoyue, Yang, Yixia, Liu, Xuelian, Wan, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864787/
https://ncbi.nlm.nih.gov/pubmed/24358111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081366
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