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HuR Function and Translational State Analysis Following Global Brain Ischemia and Reperfusion

Prolonged translation arrest in post-ischemic hippocampal CA1 pyramidal neurons precludes translation of induced stress genes and directly correlates with cell death. We evaluated regulation of mRNAs containing adenine and uridine rich elements (ARE) by assessing HuR protein and hsp70 mRNA nuclear t...

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Bibliografiske detaljer
Main Authors: Szymanski, Jeffrey J., Huang, Haihui, Jamison, Jill T., DeGracia, Donald J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864748/
https://ncbi.nlm.nih.gov/pubmed/24323414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-013-0273-2
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