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Impaired Assembly and Post-Translational Regulation of 26S Proteasome in Human End Stage Heart Failure

BACKGROUND: This study examined the hypothesis that 26S proteasome dysfunction in human end stage heart failure is associated with decreased docking of the 19S regulatory particle to the 20S proteasome. Previous studies have demonstrated that 26S proteasome activity is diminished in human end stage...

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Detalhes bibliográficos
Main Authors: Day, Sharlene M., Divald, Andras, Wang, Ping, Davis, Frank, Bartolone, Sarah, Jones, Richard, Powell, Saul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864674/
https://ncbi.nlm.nih.gov/pubmed/23515276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.000119
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