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Characterization of major peptides in Creutzfeldt-Jakob disease and scrapie.

In Creutzfeldt-Jakob disease three major peptides cosediment with the infectious agent. These distinct peptides are not present in identical fractions from uninfected brain, and bind to polyclonal antibodies raised against "prion protein" purified by protease treatment. Three similar distinct peptid...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Sklaviadis, T, Manuelidis, L, Manuelidis, E E
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386456/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3090551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.6146
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