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Clonal dissection of the human memory B cell repertoire following infection and vaccination

The analysis of the human memory B cell repertoire is of both fundamental and practical significance. We developed a simple method for the selective activation of memory B cells in total fresh or frozen PBMC using a combination of R848 and IL-2. In these conditions 30–40% of memory B cells generated...

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Bibliographic Details
Main Authors: Pinna, Debora, Corti, Davide, Jarrossay, David, Sallusto, Federica, Lanzavecchia, Antonio
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864550/
https://ncbi.nlm.nih.gov/pubmed/19404981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200839129
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