Receptor-mediated folate accumulation is regulated by the cellular folate content.

Cultured monkey kidney cells are shown to possess a cell-surface receptor that binds 5-methyltetrahydro[3',5',7,9-3H4]folic acid (5-methyltetrahydro[3H]folic acid) with high affinity (Kd = 3 nM at 4 degrees C). The cell-surface binding capacity for [3H]folic acid or [3H]methotrexate is equivalent to...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Kamen, B A, Capdevila, A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1986
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386421/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3461471/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5983
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