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Fibroblast growth factor treatment of Swiss 3T3 cells activates a subunit S6 kinase that phosphorylates a synthetic peptide substrate.

Exposure of quiescent cultures of Swiss 3T3-D1 cells to bovine brain acidic fibroblast growth factor (FGF) enhanced phosphorylation of a 31-kDa protein tentatively identified as 40S ribosomal subunit S6 (S6). Soluble extracts from FGF-treated as compared with quiescent fibroblasts exhibited up to 3-...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Pelech, S L, Olwin, B B, Krebs, E G
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386418/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3461469/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5968
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