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Treatment of human platelets with trypsin, thrombin, or collagen inhibits the pertussis toxin-induced ADP-ribosylation of a 41-kDa protein.

Permeabilization of human platelets with saponin (15-25 micrograms/ml) allows the determination of the ADP-ribosylation of a 41-kDa protein by pertussis toxin. The ADP-ribosylated protein is present in the particulate fraction. ADP-ribosylation of the 41-kDa protein increases for 20 min; it is not a...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Lapetina, E G, Reep, B, Chang, K J
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1986
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386400/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3461464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5880
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