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Single variant and multi-variant trend tests for genetic association with next generation sequencing that are robust to sequencing error

As with any new technology, next generation sequencing (NGS) has potential advantages and potential challenges. One advantage is the identification of multiple causal variants for disease that might otherwise be missed by SNP-chip technology. One potential challenge is misclassification error (as wi...

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Bibliografski detalji
Glavni autori: Kim, Wonkuk, Londono, Douglas, Zhou, Lisheng, Xing, Jinchuan, Nato, Andrew, Musolf, Anthony, Matise, Tara C., Finch, Stephen J., Gordon, Derek
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863939/
https://ncbi.nlm.nih.gov/pubmed/23594495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346824
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