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Adenovirus early region 1A protein increases the number of template molecules transcribed in cell-free extracts.

Protein encoded by adenovirus early region 1A (E1A) stimulates transcription from adenovirus promoters in vivo. Here we show that this effect can be observed in vitro. In a run-off transcription assay from the adenovirus serotype 2 (Ad2) major late promoter, extracts prepared 20 hr postinfection wer...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Leong, K, Berk, A J
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386392/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2942942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.16.5844
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