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A Novel Chimeric Adenoassociated Virus 2/Human Bocavirus 1 Parvovirus Vector Efficiently Transduces Human Airway Epithelia

Human bocavirus virus-1 (HBoV1), a newly discovered autonomous parvovirus with a 5,500 nt genome, efficiently infects human-polarized airway epithelia (HAE) from the apical membrane. We hypothesized that the larger genome and high airway tropism of HBoV1 would be ideal for creating a viral vector fo...

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Hlavní autoři: Yan, Ziying, Keiser, Nicholas W, Song, Yi, Deng, Xuefeng, Cheng, Fang, Qiu, Jianming, Engelhardt, John F
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863803/
https://ncbi.nlm.nih.gov/pubmed/23896725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.92
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