Myeloperoxidase acts as a source of free iron during steady-state catalysis by a feedback inhibitory pathway

Myeloperoxidase (MPO) is a heme-containing enzyme that generates hypochlorous acid (HOCl) from chloride (Cl(−)) and hydrogen peroxide (H(2)O(2)). It is implicated in the pathology of several chronic inflammatory conditions such as cardiovascular and pulmonary diseases and cancer. Recently we have sh...

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Autores principales: Maitra, Dhiman, Shaeib, Faten, Abdulhamid, Ibrahim, Abdulridha, Rasha M., Saed, Ghassan M., Diamond, Michael P., Pennathur, Subramaniam, Abu-Soud, Husam M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863623/
https://ncbi.nlm.nih.gov/pubmed/23624305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.04.009
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