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DNA damage response as a biomarker in treatment of leukemias

Early assessment of cancer response to the treatment is of great importance in clinical oncology. Most antitumor drugs, among them DNA topoisomerase (topo) inhibitors, target nuclear DNA. The aim of the present study was to explore feasibility of the assessment of DNA damage response (DDR) as potent...

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Detalhes bibliográficos
Main Authors: Halicka, H. Dorota, Ozkaynak, M. Fevzi, Levendoglu-Tugal, Oya, Sandoval, Claudio, Seiter, Karen, Kajstura, Malgorzata, Traganos, Frank, Jayabose, Somasunadaram, Darzynkiewicz, Zbigniew
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863585/
https://ncbi.nlm.nih.gov/pubmed/19411853
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