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Extracellular release of lymphocyte cytolytic pore-forming protein (perforin) after ionophore stimulation.

The cytolytic pore-forming protein (PFP, perforin) of lymphocyte granules has recently been isolated and characterized. The lytic activities expressed by both the isolated granules and the purified PFP require the presence of Ca2+. Here, we report on the extracellular release of PFP after stimulatio...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Young, J D, Leong, L G, Liu, C C, Damiano, A, Cohn, Z A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2426703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.15.5668
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