The snRNA-processing complex, Integrator, is required for ciliogenesis and dynein recruitment to the nuclear envelope via distinct mechanisms

We previously reported that the small nuclear RNA processing complex, Integrator, is required for dynein recruitment to the nuclear envelope at mitotic onset in cultured human cells. We now report an additional role for INT in ciliogenesis. Depletion of INT subunits from cultured human cells results...

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Detalhes bibliográficos
Main Authors: Jodoin, Jeanne N., Shboul, Mohammad, Albrecht, Todd R., Lee, Ethan, Wagner, Eric J., Reversade, Bruno, Lee, Laura A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863424/
https://ncbi.nlm.nih.gov/pubmed/24285713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20136981
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