Detection of restriction fragment length polymorphisms at the centromeres of human chromosomes by using chromosome-specific alpha satellite DNA probes: implications for development of centromere-based genetic linkage maps.

We describe a general strategy for the detection of high-frequency restriction fragment length polymorphisms in the centromeric regions of human chromosomes by molecular analysis of alpha satellite DNA, a diverse family of tandemly repeated DNA located near the centromeres of all human chromosomes....

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Willard, H F, Waye, J S, Skolnick, M H, Schwartz, C E, Powers, V E, England, S B
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3016709/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.15.5611
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