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Remodeling of insulin producing β-cells during Xenopus laevis metamorphosis

Insulin-producing β-cells are present as single cells or in small clusters distributed throughout the pancreas of the Xenopus laevis tadpole. During metamorphic climax when the exocrine pancreas dedifferentiates to progenitor cells, the β-cells undergo two changes. Insulin mRNA is down regulated at...

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Bibliographic Details
Main Authors: Mukhi, Sandeep, Horb, Marko E., Brown, Donald D.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863375/
https://ncbi.nlm.nih.gov/pubmed/19389350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.01.038
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