Limited regeneration in long acellular nerve allografts is associated with increased Schwann cell senescence

Repair of large nerve defects with acellular nerve allografts (ANAs) is an appealing alternative to autografting and allotransplantation. ANAs have been shown to be similar to autografts in supporting axonal regeneration across short gaps, but fail in larger defects due to a poorly-understood mechan...

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Main Authors: Saheb-Al-Zamani, Maryam, Yan, Ying, Farber, Scott J., Hunter, Daniel A., Newton, Piyaraj, Wood, Matthew D., Stewart, Sheila A., Johnson, Philip J., Mackinnon, Susan E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863361/
https://ncbi.nlm.nih.gov/pubmed/23644284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.04.011
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