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Effects of clodronate and alendronate on osteoclast and osteoblast co-cultures on silk-hydroxyapatite films

The goal of this study was to explore the effects of osteoporosis-related therapeutics on bone remodeling in vitro. A previously established bone-tissue mimetic system consisting of silk protein biomaterials in combination with hydroxyapatite and human cells was used for the study. Silk-hydroxyapati...

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Autori principali: Hayden, Rebecca S., Vollrath, Moritz, Kaplan, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863115/
https://ncbi.nlm.nih.gov/pubmed/24096150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.09.028
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